The energetics of weakly polar interactions in model tripeptides.

Library Generation Analysis and Combinatorial Chemistry: dedicated to Bruce Merrifield 1 Bruce Merrifield Dynamic Combinatorial Assembly of Peptide-Rhenium Coordinates: Application to the Selection of hCyp-18 inhibitors from a Library of 12 × 16 Components 3 Dynamic Combinatorial Assembly of Peptide-Rhenium Coordinates: Coordination Chemistry for Generating New Analogs of hCyp-18 Ligands 5 Oxorhenium-Mediated Cyclization and Self-Assembly of Peptides: A Combinatorial Approach for the Selection of New Ligands of the Human Cyclophilin hCyp-18 7 Thieno[3,2-e]diazepinediones and 3-Thienylimidazolidinediones Syntheses: 9 Solid-Phase Synthesis of Phosphinic Dipepetide Isosteres and β Amino Acids via Activated N-Terminal Acrylamides 11 Parallel Solid-Phase Synthesis of Macrocyclic Peptidomimetics Using Ru-Catalyzed Ring-Closing Metathesis and a New Application of Cross Metathesis 13 High Throughput Solid Phase Parallel Synthesis of Macrocyclic Peptidomimetics 15 Development of an Efficient Solid-Phase Synthetic Methodology to Construct a Combinatorial Library of a Potent HDAC Inhibitor 17 A Novel Hydrogel Functionalized with Specific Peptidomimetic Ligands for 2-D and 3-D Cell Culture 19 Application of the “Libraries from Libraries” Concept to “One-bead One-compound” Combinatorial Chemistry 21 An Appreciation of the Scientific Life and Achievements of Bruce Merrifield 23 xix